![]() The incidence of IE is approximately 3–15 per 100 000 people and is steadily increasing, due to longevity, the increased number of invasive cardiac procedures and health-care related infections. Infective endocarditis (IE) is a multisystem disease caused by an infection (usually bacterial) of the cardiac endothelium. Octapharma had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.Ĭompeting interests: The authors have declared that no competing interests exist. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.ĭata Availability: All relevant data are within the paper and its Supporting information files.įunding: Some authors (SE, MWH and HH) received an unrestricted research grant from Octapharma Benelux. ![]() Received: JanuAccepted: MaPublished: April 13, 2023Ĭopyright: © 2023 Breel et al. PLoS ONE 18(4):Įditor: Redoy Ranjan, BSMMU: Bangabandhu Sheikh Mujib Medical University, BANGLADESH (2023) Patients with infective endocarditis undergoing cardiac surgery have distinct ROTEM profiles and more bleeding complications compared to patients without infective endocarditis. ![]() Citation: Breel JS, Wensing AGCL, Eberl S, Preckel B, Schober P, Müller MCA, et al.
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